A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name PRAMEF2
Type methylation
Species Homo sapiens
Tissue bone marrow
Experiment Method qRT-pCR
Up/Down differential expression
Pro/Anti NA
Funtion Description Individual gene's expression or telomere length did not predict PD-BS but methylation of individual CpG islands did, PRAMEF2 in particular (r = 0.775). A formula based on SPARC mRNA and PRAMEF2 methylation may be used to predict remaining BM-MSC longevity
Regulation Gene PRAMEF2
Year 2017
Pubmed ID 28298930
Title Predicting the Remaining Lifespan and Cultivation-Related Loss of Osteogenic Capacity of Bone Marrow Multipotential Stromal Cells Applicable across a Broad Donor Age Range.
Drug 0
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA