| Name |
caMEK
|
| Type |
gene
|
| Species |
Rat Rattus
|
| Tissue |
rat intestinal epithelial crypt cell line IEC-6 (50)
|
| Experiment Method |
Western blot
|
| Up/Down |
NA
|
| Pro/Anti |
Pro
|
| Funtion Description |
Stable expression of caMEK but not wtMEK in HIEC led to the irreversible arrest of cellular proliferation (premature senescence)
|
| Regulation Gene |
NA
|
| Year |
2004
|
| Pubmed ID |
14701721
|
| Title |
Dual role of MEK/ERK signaling in senescence and transformation of intestinal epithelial cells.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|