| Name |
RAGE
|
| Type |
methylation
|
| Species |
Homo sapiens
|
| Tissue |
Brains were obtained within 12 h after death from 16 subjects 11 males and 5 females, aged 23-90 years
|
| Experiment Method |
bisulfite method;PCR;direct sequencing of PCR products.
|
| Up/Down |
Down
|
| Pro/Anti |
NA
|
| Funtion Description |
The total number of methylcytosines significantly decreased with age. While the number of methylated cytosines at CpG dinucleotides was stable throughout adult life, that at sites other than CpG dinucleotides significantly decreased with age in cases >/=7
|
| Regulation Gene |
RAGE
|
| Year |
1999
|
| Pubmed ID |
10036314
|
| Title |
Decrease with age in methylcytosines in the promoter region of receptor for advanced glycated end products (RAGE) gene in autopsy human cortex.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|