A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name RARB2 promoter
Type methylation
Species Homo sapiens
Tissue normal adult colon tissues
Experiment Method qPCR
Up/Down Down
Pro/Anti Pro
Funtion Description RARbeta2 methylation was also observed in normal colon tissues and was lower in young individuals than in older ones (mean, 11% versus 23%; P < 0.05). The adult RARbeta2 isoform also shows age-related methylation in normal tissues but more variable methyl
Regulation Gene RARbeta2
Year 2004
Pubmed ID 14726683
Title Methylation and regulation of expression of different retinoic acid receptor beta isoforms in human colon cancer
Drug NA
Disease colorectal cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA