A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name RASSF1A promoter
Type methylation
Species Homo sapiens
Tissue normal prostate peripheral zone tissue
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description We found a significant increase in promoter methylation to correlate with age for the CpG islands at RARB2 (r = 0.4; P < 0.0001), RASSF1A (r = 0.27; P = 0.01), GSTP1 (r = 0.59; P < 0.0001), NKX2-5 (r = 0.27; P = 0.008), and ESR1 (r = 0.244; P = 0.024).
Regulation Gene RASSF1A
Year 2007
Pubmed ID 17606710
Title Age-Related DNA Methylation Changes in Normal Human Prostate Tissues
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA