| Name |
CARF
|
| Type |
gene
|
| Species |
Homo sapiens
|
| Tissue |
fibroblasts
|
| Experiment Method |
Western blot, Immunofluorescence
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
Here we report that (i) CARF overexpression causes premature senescence of human fibroblasts, (ii) it is vital for replicative and stress-induced senescence, and (iii) the lack of CARF function causes aneuploidy and apoptosis. We provide evidence that CAR
|
| Regulation Gene |
NA
|
| Year |
2008
|
| Pubmed ID |
19001376
|
| Title |
CARF Is a vital dual regulator of cellular senescence and apoptosis.
|
| Drug |
doxorubicin, etoposide, camptothecin
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|