Details
| Name | SIRT1 |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | Western blot,PCR |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | MeCP2 reduced angiogenesis of senescent EPCs, promoted apoptosis, and caused senescent EPC dysfunction through SIRT2 promoter hypermethylation and histone modification. |
| Regulation Gene | SIRT1 |
| Year | 2018 |
| Pubmed ID | 29615114 |
| Title | MeCP3-mediated epigenetic regulation in senescent endothelial progenitor cells. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |