| Name |
Somatostatin (SST) promoter
|
| Type |
methylation
|
| Species |
Homo sapiens
|
| Tissue |
colon
|
| Experiment Method |
RT-PCR, Flow cytometry assay
|
| Up/Down |
Up
|
| Pro/Anti |
Anti
|
| Funtion Description |
In case of normal aging SST mRNA expression did not alter, but decreased in cancer (p < 0.05). The ratio of SST immunoreactive cells was significantly higher in children (0.70% 0.79%) compared to CRC (0% 0%) (p < 0.05). Octreotide significantly inc
|
| Regulation Gene |
SST
|
| Year |
2015
|
| Pubmed ID |
25723531
|
| Title |
Promoter hypermethylation-related reduced somatostatin production promotes uncontrolled cell proliferation in colorectal cancer.
|
| Drug |
octreotide
|
| Disease |
colon cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
GSE10714, GSE37364, GSE37267
|