| Name |
SOX1 promoter
|
| Type |
methylation
|
| Species |
Homo sapiens
|
| Tissue |
nasopharynx
|
| Experiment Method |
qRT-PCR, Flow cytometry assay, Western blot, Immunofluorescence
|
| Up/Down |
Up
|
| Pro/Anti |
Anti
|
| Funtion Description |
Down-regulation of SOX1 was detected in NPC cell lines and tissues.Besides, quantitative methylation-specific polymerase chain reaction revealed that SOX1 promoter was hypermethylated in NPC cell lines.Restoration of SOX1 expression significantly reduced
|
| Regulation Gene |
SOX
|
| Year |
2015
|
| Pubmed ID |
25427424
|
| Title |
SOX1 down-regulates B-catenin and reverses malignant phenotype in nasopharyngeal carcinoma.
|
| Drug |
0
|
| Disease |
nasopharyngeal carcinoma (NPC)
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|