A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CARF
Type gene
Species Homo sapiens
Tissue SKOV-3;HeLa;U2OS;SaOS-2; MCF-7; MDA-MB-231;T47D;G361 ;HT-1080 ;HUH-6;HUH-7;DLD-1;H-1299;A549
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description CARF (Collaborator of ARF)/CDKN2AIP was discovered as a novel ARF-binding protein. It has been established as an essential cell survival, p53-, and cell proliferation-regulatory protein. Although a moderate upregulation of CARF caused growth arrest and se
Regulation Gene NA
Year 2018
Pubmed ID 29748568
Title CARF enrichment promotes epithelial-mesenchymal transition via Wnt/B-catenin signaling: its clinical relevance and potential as a therapeutic target
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA