A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name SOX9
Type methylation
Species Mus musculus
Tissue Cartilage
Experiment Method ChIP
Up/Down Down
Pro/Anti Anti
Funtion Description Histone 3 lysine 4 dimethylation (H3K4me2, a histone modification for transcriptional activation) in the Sox9 promoter region was decreased with age, which was associated with the age-dependent decrease in SOX9 expression in ACs.
Regulation Gene Sox9
Year 2016
Pubmed ID 26806292
Title Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA