| Name |
SRD5A2 promoter
|
| Type |
methylation
|
| Species |
Homo sapiens
|
| Tissue |
prostate
|
| Experiment Method |
ChiP, Luciferase reporter assay
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
Furthermore, we show that increasing age in mice and humans is associated with increased methylation of the SRD5A2 promoter and concomitantly decreased protein expression.Artificial induction of inflammation in prostate primary epithelial cells leads to h
|
| Regulation Gene |
SRD5A2
|
| Year |
2015
|
| Pubmed ID |
25700986
|
| Title |
DNA methyl transferase 1 reduces expression of SRD5A2 in the aging adult prostate.
|
| Drug |
5-aza-20-deoxycytide
|
| Disease |
benign prostatic hyperplasia
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|