Details
| Name | TERT promoter |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | bone |
| Experiment Method | PCR, Western blot |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | We have shown that RG108 significantly induces the expression of TERT by blocking methylation at the TERT promoter region. Thus, these data indicate that an optimized dose of RG108 may improve the cell migration, protection, cellular senescence, which |
| Regulation Gene | TERT |
| Year | 2015 |
| Pubmed ID | 25952632 |
| Title | Anti-senescence effects of DNA methyltransferase inhibitor RG108 in human bone marrow mesenchymal stromal cells. |
| Drug | RG108 |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |