A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name X chromosome
Type methylation
Species Mus musculus
Tissue Brains
Experiment Method oxidative bisulfite sequencing,qPCR ,Digital PCR,Immunoblotting,Repeat element pyrosequencing
Up/Down NA
Pro/Anti NA
Funtion Description While the hypothesis of down-regulated DNMT and TET expression with aging and subsequent decreases in total levels of mC and/or hmC is seductive, the findings presented here provide extensive evidence that this is not the case in the murine hippocampus. R
Regulation Gene NA
Year 2016
Pubmed ID 27413395
Title Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA