Details
| Name | ZEB1 |
| Type | methylation |
| Species | Mus musculus |
| Tissue | breast |
| Experiment Method | RT-PCR |
| Up/Down | differential expression |
| Pro/Anti | NA |
| Funtion Description | PRMT1 impacted EMT process and cellular senescence by mediating the asymmetric dimethylation of arginine 3 of histone H4 (H4R3me2as) at the ZEB1 promoter to activate its transcription, indicating the essential roles of this epigenetic control both in EMT |
| Regulation Gene | ZEB1 |
| Year | 2016 |
| Pubmed ID | 26813495 |
| Title | The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1. |
| Drug | NA |
| Disease | breast cancer |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |