A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name let-7
Type miRNA
Species Homo sapiens
Tissue muscle
Experiment Method RT-PCR,Western blot
Up/Down Up
Pro/Anti Pro
Funtion Description a reduced cell proliferation potential and the consequent regeneration failure of aging muscle have been shown to be governed by lethal-7 ( let-7) microRNA-mediated mechanisms
Regulation Gene IL-6
Year 2019
Pubmed ID 30860873
Title Aging-associated genes and let-7 microRNAs: a contribution to myogenic program dysregulation in oculopharyngeal muscular dystrophy.
Drug NA
Disease Oculopharyngeal muscular dystrophy (OPMD)
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA