| Name |
miR-101
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
endometrial
|
| Experiment Method |
qRT-PCR,TUNEL staining,Senescence assay (SA-B-gal staining),Western blot,Microarray,Luciferase activity assay,IHC
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Importantly, further results suggest an inverse correlation between low miR-101 and high EZH2, MCL-1 and FOS expression in EC specimens. We conclude that, as a crucial tumor suppressor, microRNA-101 suppresses cell proliferation, invasiveness and self-ren
|
| Regulation Gene |
EZH2,MCL-1,FOS
|
| Year |
2015
|
| Pubmed ID |
25153722
|
| Title |
MicroRNA-101 targets EZH2, MCL-1 and FOS to suppress proliferation, invasion and stem cell-like phenotype of aggressive endometrial cancer cells.
|
| Drug |
NA
|
| Disease |
endometrial cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|