A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-101
Type miRNA
Species Homo sapiens
Tissue Human Diploid Fibroblasts (HDF)
Experiment Method qRT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description Ezh2 is regulated by miR-101 in human fibroblasts, and found that both overexpression of miR-101 and downregulation of Ezh2 independently induce senescence in the absence of UVB irradiation. However, the downregulation of miR-101 was not sufficient to blo
Regulation Gene Ezh2
Year 2013
Pubmed ID 23557329
Title Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA