| Name |
miR-101b
|
| Type |
miRNA
|
| Species |
Mus musculus
|
| Tissue |
NA
|
| Experiment Method |
quantitative real-time PCR,Western blot,ChIP,Dual-Luciferase reporter assay
|
| Up/Down |
Up
|
| Pro/Anti |
anti
|
| Funtion Description |
This demonstrated that HDAC suppressed the expression of miR-101b and miR-26b in the LPS-treated macrophages of aged mice and contributed to the aging process. TSA-induced increased expression of miR-101b and miR-26b could further suppress COX-2 expressio
|
| Regulation Gene |
COX-2
|
| Year |
2015
|
| Pubmed ID |
26371058
|
| Title |
Dysregulated expression of miR-101b and miR-26b lead to age-associated increase in LPS-induced COX-2 expression in murine macrophage.
|
| Drug |
LPS
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|