| Name |
miR-107
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
NA
|
| Experiment Method |
SA-B gal flow cytometry assay,RPTOR,qRT-PCR,
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Our findings revealed that miR-107 was downregulated in prolonged low dose rapamycin-induced delayed senescence in HUVECs whereas its over-expression induced cell cycle arrest at G0/G1 phase and increased expression of P16INK4A, a cellular senescence mark
|
| Regulation Gene |
PTEN
|
| Year |
2018
|
| Pubmed ID |
29857052
|
| Title |
Endothelial replicative senescence delayed by the inhibition of MTORC1 signaling involves MicroRNA-107.
|
| Drug |
rapamycin
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|