| Name |
miR-124
|
| Type |
miRNA
|
| Species |
Mus musculus
|
| Tissue |
kidney, lung, liver, heart, and brain
|
| Experiment Method |
RT-qPCR,microarray,Senescence-associated B-galactosidase staining,Western blot,Luciferase reporter assay
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
In addition to the vital role of miR-124 in neurogenesis (Papagiannakopoulos & Kosik, 2009), miR-124 has been established to be a typical tumor suppressor in diverse human cancers, including lung cancer, prostate cancer, cholangiocarcinoma, and colorectal
|
| Regulation Gene |
CCNA2
|
| Year |
2019
|
| Pubmed ID |
30848072
|
| Title |
The p53/miRNAs/Ccna2 pathway serves as a novel regulator of cellular senescence: Complement of the canonical p53/p21 pathway
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|