A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-124
Type miRNA
Species Homo sapiens
Tissue skin
Experiment Method real-time PCR,Senescence-associated B-galactosidase (SA- B-Gal) activity
Up/Down Up
Pro/Anti Pro
Funtion Description Forced overexpression of miR-124 as a result of the transfection of a miR-124 mimic in A431 resulted in the significant suppression of the proportion of cancer cells. The current results indicated that miR-124 increases as a result of cell senescence and
Regulation Gene NA
Year 2017
Pubmed ID 27818465
Title The expression of miR-124 increases in aged skin to cause cell senescence and it decreases in squamous cell carcinoma.
Drug NA
Disease squamous carcinoma
Environment Factors UV irradiation
Circulating NA
Variant NA
High-throughput NA