Details
| Name | miR-124 |
| Type | miRNA |
| Species | Caenorhabditis elegans |
| Tissue | NA |
| Experiment Method | qRT-PCR |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | Mice lacking the helicase domain of the WRN ortholog exhibit many phenotypic features of WS, including a pro-oxidant status and a shorter mean life span.Caenorhabditis elegans (C. elegans) with a nonfunctional wrn-1 DNA helicase also exhibit a shorter lif |
| Regulation Gene | NA |
| Year | 2012 |
| Pubmed ID | 23075628 |
| Title | Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging |
| Drug | Vitamin C |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |