A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-125a-5p
Type miRNA
Species Mus musculus
Tissue NA
Experiment Method luciferase assay,RNA isolation and mRNA expression analysis,MicroRNA microarray,Immunoblot analysis
Up/Down Down
Pro/Anti NA
Funtion Description We propose that miR-125a-5p dependent downregulation of Stat3, Casp2, and Stard13 contributes to the calorie restriction-mediated delay of aging.
Regulation Gene Stat3,Casp2,Stard13
Year 2017
Pubmed ID 28783714
Title Aging and calorie restriction regulate the expression of miR-125a-5p and its target genes Stat3, Casp2 and Stard13
Drug NA
Disease NA
Environment Factors caloric restriction (CR)
Circulating NA
Variant NA
High-throughput NA