| Name |
miR-125b
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
brain
|
| Experiment Method |
qRT-PCR,Western blotting,Immunofluorescence staining,
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Overexpression of miR-125b in pediatric low grade glioma (PLGG) derived cell lines (Res186, Res259, and BT66) resulted in decreased growth and invasion, as well as apoptosis. Additionally, miR-125b overexpression in BT66 resulted in senescence.
|
| Regulation Gene |
BBC3,BMF
|
| Year |
2018
|
| Pubmed ID |
30131528
|
| Title |
MicroRNA (miR) 125b regulates cell growth and invasion in pediatric low grade glioma.
|
| Drug |
NA
|
| Disease |
Pediatric low-grade glioma (PLGG)
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|