A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-125b
Type miRNA
Species Homo sapiens
Tissue liver
Experiment Method Western blot,qRT-PCR,Immunohistochemistry,Luciferase assay,SA-B-gal assay
Up/Down Up
Pro/Anti Pro
Funtion Description we identified that miR-125b can suppress the expression of SIRT6 by directly targeting the seed-matching region of its 3'UTR.
Regulation Gene SIRT6
Year 2018
Pubmed ID 30034937
Title MiR-125b attenuates human hepatocellular carcinoma malignancy through targeting SIRT6.
Drug NA
Disease hepatocarcinoma
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA