A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-1260b
Type miRNA
Species Homo sapiens
Tissue lung
Experiment Method real-time PCR,SA-B-gal staining,Luciferase report assay,Western blotting,ChIP
Up/Down Up
Pro/Anti anti
Funtion Description Functionally, miR-1260b overexpression promoted cell proliferation and cell cycle, conversely inhibited cell apoptosis and senescence.
Regulation Gene SOCS6
Year 2019
Pubmed ID 30737371
Title miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate cell proliferation and apoptosis in NSCLC.
Drug NA
Disease non-small cell lung cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA