A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-133a
Type miRNA
Species Mus musculus
Tissue internal anal sphincter (IAS) smooth muscle (SM)
Experiment Method miRNA microarrays,Immunocytochemical analysis,Immunoblot analysis
Up/Down Up
Pro/Anti anti
Funtion Description Regardless, it is well known that miRNA-133a negatively regulates RhoA; downregulation of miR-133a promotes the proliferation, migration, and contraction, whereas its upregulation has the opposite effect, by targeting Rhoa
Regulation Gene NA
Year 2016
Pubmed ID 27634012
Title Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA