| Name |
miR-135a
|
| Type |
miRNA
|
| Species |
Mus musculus
|
| Tissue |
NA
|
| Experiment Method |
qRT-PCR,Senescence-associated B-galactosidase staining,MTT,Western blot,Luciferase assay
|
| Up/Down |
Down
|
| Pro/Anti |
anti
|
| Funtion Description |
Overexpression of miR-135a in young TSPCs suppresses senescence, promotes proliferation, and induces migration and tenogenic differentiation, whereas suppression of miR-135a in aged TSPCs has the opposite effects.
|
| Regulation Gene |
ROCK1
|
| Year |
2015
|
| Pubmed ID |
25460182
|
| Title |
miR-135a modulates tendon stem/progenitor cell senescence via suppressing ROCK1.
|
| Drug |
NA
|
| Disease |
age-related tendon disorders
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|