A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CAT
Type gene
Species Dog
Tissue Heart
Experiment Method DNA microarray analyses
Up/Down Up
Pro/Anti Anti
Funtion Description Moderate overexpression of Sirt1 protected the heart from oxidative stress induced by paraquat, with increased expression of antioxidants, such as catalase, through forkhead box O (FoxO)-dependent mechanisms, whereas high levels of Sirt1 increased oxidati
Regulation Gene NA
Year 2007
Pubmed ID 17446436
Title Sirt1 regulates aging and resistance to oxidative stress in the heart.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA