A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-141
Type miRNA
Species Homo sapiens
Tissue bone
Experiment Method qRT-PCR,Western blot,AGO2 immunoprecipitation,
Up/Down Down
Pro/Anti anti
Funtion Description The expression levels of miR-141 are positively correlated with BMD and negatively correlated with the aging of bones in both aged rhesus monkeys (Macaca mulatta) and osteoporotic patients.
Regulation Gene Calcr,EphA2
Year 2018
Pubmed ID 29852535
Title Suppression of Bone Resorption by miR-141 in Aged Rhesus Monkeys.
Drug NA
Disease age-related osteoporosis
Environment Factors cold
Circulating NA
Variant NA
High-throughput NA