A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-143
Type miRNA
Species Mus musculus
Tissue muscle
Experiment Method Real-Time PCR and Western blotting
Up/Down Down
Pro/Anti Pro
Funtion Description Moreover, we show that downregulation of miR-143 during aging may act as a compensatory mechanism aiming at improving myogenesis efficiency; however, concomitant upregulation of miR-143 target gene, Igfbp5, is associated with increased cell senescence, th
Regulation Gene Igfbp5
Year 2016
Pubmed ID 26762731
Title Age-related changes in miR-143-3p:Igfbp5 interactions affect muscle regeneration
Drug NA
Disease defective regeneration of skeletal muscle
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA