A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-145
Type miRNA
Species Homo sapiens
Tissue hepatic stellate cells
Experiment Method Immunofluorescence analysis,Luciferase reporter assay,qRT-PCR,Western blot
Up/Down Up
Pro/Anti Pro
Funtion Description induces the senescence of activated hepatic stellate cells through the activation of p53 pathway by ZEB2
Regulation Gene ZEB2
Year 2019
Pubmed ID 30479019
Title MicroRNA-145 induces the senescence of activated hepatic stellate cells through the activation of p53 pathway by ZEB2.
Drug NA
Disease liver fibrosis
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA