A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-145
Type miRNA
Species Homo sapiens
Tissue peritonea
Experiment Method microarray,RT-PCR,Luciferase target assay,Lysate preparation and immunoblotting analyses,SA-B-gal staining,Immunohistochemistry
Up/Down Up
Pro/Anti Pro
Funtion Description The main effector mechanism of the clonogenic death induced by mir-145 was that of accelerated senescence.
Regulation Gene 4-Oct
Year 2015
Pubmed ID 24240684
Title Protumorigenic effects of mir-145 loss in malignant pleural mesothelioma.
Drug NA
Disease Malignant Pleural Mesothelioma
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA