A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CAT
Type gene
Species Mus musculus
Tissue NA
Experiment Method Transgenic,other
Up/Down Up
Pro/Anti Anti
Funtion Description To test the free radical theory of aging in mice, and particularly the notion that mitochondria are important sources and targets of ROS damage, transgenic mice were generated that express mitochondrially targeted catalase (MCAT). Median and maximum life
Regulation Gene NA
Year 2008
Pubmed ID 18772469
Title Reduction of age-associated pathology in old mice by overexpression of catalase in mitochondria.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA