A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-146a
Type miRNA
Species Homo sapiens
Tissue Endothelial cells
Experiment Method qRT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description Among the 367 profiled miRs in HUVECs, miR-146a, miR-9, miR-204 and miR-367 showed the highest up-regulation in senescent cells. Their predicted target genes belong to nine common pathways, including Toll-like receptor signalling (TLR) that plays a pivota
Regulation Gene IRAK1;TRAF6
Year 2012
Pubmed ID 22692818
Title MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput GSE37972