A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-146a
Type miRNA
Species Homo sapiens
Tissue Eyes;Cornea Rings
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description RS of HTM cells was associated with significant changes in expression of 18 miRNAs, including the upregulation of miR-146a. miR-146a downregulated multiple genes associated with inflammation, including IRAK1, IL6, IL8, and PAI-1, inhibited senescence-asso
Regulation Gene NA
Year 2010
Pubmed ID 20053980
Title Modulation of Inflammatory Markers by miR-146a during Replicative Senescence in Trabecular Meshwork Cells
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA