A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-146a
Type miRNA
Species Homo sapiens
Tissue HCA2
Experiment Method RT-PCR,Northern Blot,Western Blots
Up/Down Up
Pro/Anti NA
Funtion Description Senescence is a cellular program that irreversibly arrests the proliferation of damaged cells and induces the secretion of the inflammatory mediators IL- 6 and IL-8 which are part of a larger senescence associated secretory phenotype (SASP). We screened q
Regulation Gene IRAK1
Year 2009
Pubmed ID 20148189
Title MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA