A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-155
Type miRNA
Species Mus musculus
Tissue NA
Experiment Method Quantitative RT-PCR,luciferase assay
Up/Down Down
Pro/Anti anti
Funtion Description In summary, we provide data supporting a novel mechanism contributing to vasoconstriction in the aging vasculature in which SMC-MR suppression of miR-155 enhances LTCC and AngII signaling in resistance vessels.
Regulation Gene LTCC,AgtR1
Year 2016
Pubmed ID 27683672
Title Vascular mineralocorticoid receptor regulates microRNA-155 to promote vasoconstriction and rising blood pressure with aging
Drug NA
Disease hypertension
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA