A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-17-92
Type miRNA
Species Homo sapiens
Tissue In mammalian cells
Experiment Method PCR,Western Blot
Up/Down Up
Pro/Anti Anti
Funtion Description The miR-17-92 gene cluster, a polycistron encoding six microRNAs (miRNA), is frequently overexpressed in human cancers and has been shown to promote several aspects of oncogenic transformation, including evasion of apoptosis. In the current study, we show
Regulation Gene WAF1
Year 2010
Pubmed ID 20851997
Title The miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescence.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA