A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name cbp-1
Type gene
Species Caenorhabditis elegans
Tissue NA
Experiment Method PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description The gene cbp-1, encoding the worm ortholog of p300/CBP (CREB-binding protein), is one of the very few key genes known to be essential for lifespan doubling under axenic dietary restriction (ADR). By using tissue-specific RNAi, we found that cbp-1 expressi
Regulation Gene NA
Year 2017
Pubmed ID 29099917
Title CBP-1 acts in GABAergic neurons to double lifespan
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA