| Name |
miR-184
|
| Type |
miRNA
|
| Species |
Mus musculus
|
| Tissue |
kidney
|
| Experiment Method |
miRNA microarrays,quantitative real-time PCR,SA-B-gal staining,Western blotting,Dual luciferase report assay
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
However, miR-184 and miR-150 inhibitors promoted autophagy and reduced oxidative damage by upregulating Rab1a and Rab31 in old GMCs. In conclusion, miR-184 and miR-150 inhibited autophagy, promoting GMC aging.
|
| Regulation Gene |
Rab1a,Rab31
|
| Year |
2015
|
| Pubmed ID |
26165933
|
| Title |
miR-184 and miR-150 promote renal glomerular mesangial cell aging by targeting Rab1a and Rab31.
|
| Drug |
NA
|
| Disease |
kidney aging
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|