Details
| Name | miR-191 |
| Type | miRNA |
| Species | Homo sapiens |
| Tissue | Blood |
| Experiment Method | PCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | Endothelial senescence is thought to play a role in CAD (coronary artery disease). miR-34a (microRNA-34a) and other SIRT1 (silent information regulator 1)-related miRs have recently been found to target SIRT1 leading to endothelial senescence. |
| Regulation Gene | SIRT1 |
| Year | 2012 |
| Pubmed ID | 22364258 |
| Title | MicroRNA-34a regulates the longevity-associated protein SIRT1 in coronary artery disease: effect of statins on SIRT1 and microRNA-34a expression |
| Drug | Statins |
| Disease | NA |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | NA |
| High-throughput | NA |