| Name |
miR-195
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
bone
|
| Experiment Method |
Q-FISH,RT-PCR,miRNA microarray,Luciferase activity assay,Senescence-associated B-galactosidase (gal) staining,Western blot
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
Notably, abrogation of miR-195 markedly restored proliferative abilities in OMSCs. Transplantation of OMSCs with knocked out miR-195 reduced infarction size and improved LV function. In conclusion, rejuvenation of aged stem cells by miR-195 inhibition wou
|
| Regulation Gene |
Tert
|
| Year |
2016
|
| Pubmed ID |
26390028
|
| Title |
Abrogation of Age-Induced MicroRNA-195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|