A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-19b-3p
Type miRNA
Species Goat
Tissue dairy goat testes
Experiment Method Dual luciferase analysis, Immunofluorescence staining,Real time QPCR analysis,Western blot,SA-B-gal staining
Up/Down NA
Pro/Anti anti
Funtion Description The expression of the phosphorylated protein kinase B (pAKT) and phosphorylated ribosomal protein S6 (pS6) were increased in the presence of miR-19b-3p which suggest that miR19b-3p activated p-AKT and phosphor-S6 ribosomal protein through PLZF to regulate
Regulation Gene PLZF
Year 2018
Pubmed ID 29171024
Title miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA