Details
| Name | miR-200c |
| Type | miRNA |
| Species | Homo sapiens |
| Tissue | HUVEC |
| Experiment Method | RT-PCR,Western blot |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | miR-200c overexpression induced HUVEC growth arrest, apoptosis and senescence; these phenomena were also induced by H2O2 and were partially rescued by miR-200c inhibition. Moreover, miR-200c target ZEB1 messenger RNA and protein were downmodulated by H2O2 |
| Regulation Gene | ZEB1 |
| Year | 2011 |
| Pubmed ID | 21527937 |
| Title | miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |