A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-203
Type miRNA
Species Mus musculus
Tissue NA
Experiment Method Western blotting,qRT-PCR
Up/Down NA
Pro/Anti Pro
Funtion Description Thus, the age-induced increase in miR-203 may be caused by epigenetic promoter hypomethylation in the aorta. These findings indicate that miR-203 promotes a re-programming of Src/ERK signalling pathways in vascular smooth muscle, impairing the regulation
Regulation Gene NA
Year 2017
Pubmed ID 27502584
Title MicroRNA-203 mimics age-related aortic smooth muscle dysfunction of cytoskeletal pathways
Drug NA
Disease Increased aortic stiffness
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA