A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CCN1
Type gene
Species Homo sapiens
Tissue CRL-2522;CCL-186
Experiment Method RT-PCR;Western blot;RNAi
Up/Down Up
Pro/Anti Pro
Funtion Description The matricellular protein CCN1 (also known as CYR61; cysteine-rich protein 61), which is dynamically expressed at sites of wound repair, can induce fibroblast senescence by binding to integrin alpha(6)beta(1) and the heparan sulphate proteoglycans (recept
Regulation Gene NA
Year 2010
Pubmed ID 20526329
Title The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA