A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-21
Type miRNA
Species Homo sapiens
Tissue brain
Experiment Method RT-q PCR,Western blotting,Dual- luciferase reporter assay,Beta- galactosidase (B- Gal) staining,MTT
Up/Down Down
Pro/Anti anti
Funtion Description MicroRNA-21 might promote cell proliferation and inhibit cell senescence and apoptosis of human glioma cells by targeting SPRY1 via the PTEN/PI3K/AKT signaling pathway.
Regulation Gene SPRY1
Year 2018
Pubmed ID 29316313
Title MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting SPRY1 via the PTEN/PI3K/AKT signaling pathway.
Drug NA
Disease glioma
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA