A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-21
Type miRNA
Species Mus musculus
Tissue MEF
Experiment Method Western blot
Up/Down Up
Pro/Anti Pro
Funtion Description MicroRNA-21 (miR-21) is overexpressed virtually in all human cancers and displays oncogenic activity in a transgenic murine model. Similarly, the p53 tumor suppressor gene is the most frequently mutated gene in human cancer, and its loss or mutation leads
Regulation Gene NA
Year 2013
Pubmed ID 23385064
Title Interaction of the oncogenic miR-21 microRNA and the p53 tumor suppressor pathway
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA